Preparation

This section offers techniques for preparing and administering Sandostatin^® LAR^® (octreotide/IM injection).

Convenient packaging

Sandostatin LAR is available in 3 strengths:

• 10 mg (dark blue package)
• 20 mg (orange package)
• 30 mg (dark red package)

Each package is a single-use kit. Before administering Sandostatin LAR, check to make sure that all the contents are intact.

Kits include:

• One vial containing Sandostatin LAR
• Two vials containing diluent or, 1 new, prefilled vehicle 5-mL syringe that offers greater ease and convenience in preparing Sandostatin LAR
• Two 40-mm (1½") 19- or 20-gauge needles
• Instruction booklet

Storage considerations

Sandostatin LAR should be refrigerated, especially for prolonged use. Sandostatin LAR should be stored at temperatures of 2°C to 8°C and protected from light until time of use.

Before administration, Sandostatin LAR should be allowed to reach room temperature, which may take 30 to 60 minutes. After preparation of the suspension, the drug must be administered immediately.

Caution: Sandostatin LAR must be protected from high temperatures, including temporary storage areas that may become hot (eg, warehouses or car interiors). Because octreotide acetate is uniformly distributed within microspheres of a slow-release, biodegradable polymer, temperatures above 41°C will cause the product to melt. If Sandostatin LAR reaches 41°C, it will be impossible to achieve suspension of the powder in the diluent, and the product must be discarded.

Click here to read about mixing Sandostatin LAR